| Investor | Value | Of portfolio | Shares | Change | Quarter |
|---|---|---|---|---|---|
| Maverick Capital · Lee Ainslie | $59.7M | 0.53% | 10.28M | +1.1% | Q2 2026 |
| Renaissance Technologies | $9.9M | 0.01% | 1.70M | +185% | Q2 2026 |
| Duquesne Family Office · Stanley Druckenmiller | $1.0M | 0.02% | 173.00K | — | Q2 2026 |
From each investor's quarterly 13F filing with the SEC: positions at the quarter's end, reported up to 45 days later. All investors
No member of Congress has disclosed a WVE trade since 2025.
From House and Senate STOCK Act reports. Members disclose trades, not holdings, as value ranges up to 45 days later, so amounts are estimates and “last move” is a hint at who still holds it, not a position. All recent congress trades
| Date | Insider | Transaction | Shares | Value |
|---|---|---|---|---|
| Aug 11, 2026 | Rawcliffe AdrianDirector | Sale at price 5.29 per share. | 12.7K | $67.18K |
| Aug 10, 2026 | Wagner Heidi LDirector | Conversion of Exercise of derivative security at price 5.97 per share. | 7K | $41.79K |
| Aug 10, 2026 | Wagner Heidi LDirector | Sale at price 6.01 per share. | 7K | $42.07K |
| Aug 10, 2026 | Takanashi KenDirector | Sale at price 6.01 per share. | 3.9K | $23.22K |
| Aug 10, 2026 | Tan Aik NaDirector | Sale at price 6.01 per share. | 432 | $2.60K |
| Mar 29, 2026 | Ra Capital Management, L.P.Beneficial Owner of more than 10% of a Class of Security | Purchase at price 6.06 - 6.50 per share. | 8.77M | $54.62M |
| Mar 22, 2026 | Takanashi KenDirector | — | 3.90M | — |
| Feb 25, 2026 | Francis Christopher JohnOfficer | Conversion of Exercise of derivative security at price 3.87 - 4.75 per share. | 33.2K | $141.92K |
| Feb 25, 2026 | Francis Christopher JohnOfficer | Sale at price 15.00 - 15.09 per share. | 33.2K | $499.59K |
| Feb 8, 2026 | Moran KyleChief Financial Officer | Sale at price 13.45 per share. | 3.6K | $48.26K |
| Feb 8, 2026 | Bolno Paul B. M.D.Chief Executive Officer | Sale at price 13.45 per share. | 10.5K | $140.96K |
| Feb 8, 2026 | Vargeese ChandraOfficer | Sale at price 13.45 per share. | 3.2K | $43.42K |
| Feb 8, 2026 | Francis Christopher JohnOfficer | Sale at price 13.45 per share. | 1.9K | $25.33K |
| Feb 4, 2026 | Francis Christopher JohnOfficer | — | 38.8K | — |
| Feb 4, 2026 | Moran KyleChief Financial Officer | — | 45.6K | — |
| Feb 4, 2026 | Bolno Paul B. M.D.Chief Executive Officer | — | 165K | — |
| Feb 4, 2026 | Vargeese ChandraOfficer | — | 45.6K | — |
| Jan 1, 2026 | Francis Christopher JohnOfficer | Conversion of Exercise of derivative security at price 3.14 per share. | 9.4K | $29.44K |
| Jan 1, 2026 | Francis Christopher JohnOfficer | Sale at price 15.92 - 16.70 per share. | 9.4K | $150.26K |
| Dec 10, 2025 | Gsk PlcBeneficial Owner of more than 10% of a Class of Security | Purchase at price 19.00 per share. | 1.47M | $27.93M |
| Year | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Year |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | -23.9 | 7.7 | -48.0 | -2.6 | -6.8 | -11.7 | -5.2 | -11.1 | -24.5 | -16.4 | −81.8% | ||
| 2025 | -6.5 | -8.6 | -23.6 | -4.5 | -22.2 | 8.2 | 24.6 | 18.5 | -23.8 | 23.5 | -14.2 | 119.1 | +37.4% |
| 2024 | -14.5 | 11.3 | 28.3 | -20.1 | 25.4 | -19.3 | 32.5 | -13.2 | 42.9 | 67.2 | 10.1 | -18.1 | +145.0% |
| 2023 | -29.6 | -14.8 | 3.1 | -7.9 | -0.8 | -8.1 | 20.1 | -0.5 | 32.2 | -6.4 | -1.3 | -4.9 | −27.9% |
| 2022 | -30.3 | 12.3 | -18.7 | -2.5 | -28.2 | 132.1 | -21.8 | 16.9 | 21.5 | 32.7 | -11.5 | 65.1 | +122.9% |
| 2021 | 29.2 | -7.5 | -40.4 | 9.6 | 11.2 | -2.6 | -17.3 | 14.9 | -22.6 | -6.3 | -15.0 | -19.5 | −60.1% |
| 2020 | -11.5 | 18.9 | 11.0 | -7.4 | 17.3 | 2.3 | -15.7 | 42.7 | -32.2 | -16.7 | 24.8 | -10.8 | −1.9% |
| 2019 | -11.4 | 12.6 | -7.3 | -31.7 | -13.6 | 13.8 | -17.9 | 7.4 | -10.7 | 23.2 | 31.1 | -75.8 | −80.9% |
| 2018 | 14.0 | 27.4 | -21.3 | 10.8 | 4.7 | -17.8 | 5.6 | 31.9 | -6.2 | -6.6 | 2.5 | -12.1 | +19.8% |
| 2017 | 9.9 | 4.7 | -8.6 | -23.3 | -10.4 | -1.6 | 6.7 | 18.4 | -7.4 | 6.0 | 61.4 | -5.6 | +34.2% |
| 2016 | -15.2 | 11.2 | -7.8 | -2.6 | 17.7 | 30.0 | -6.7 | 29.2 | 30.2 | -1.9 | 11.8 | -26.5 | +63.9% |
| 2015 | -1.8 | −1.8% |
Wave Life Sciences, Inc., a clinical-stage biotechnology company, focuses on unlocking the potential of ribonucleic acid (RNA) medicines to transform human health. Its RNA medicines platform, PRISM, combines RNA medicine modalities, chemistry innovation, and deep insights in human genetics to deliver scientific breakthroughs that treat rare and common disorders. Its pipeline focuses on obesity (WVE-007), alpha-1 antitrypsin deficiency (AATD) (WVE-006), and PNPLA3 I148M liver disease (WVE-008) programs; and clinical programs for Duchenne muscular dystrophy and Huntington's disease, as well as various preclinical programs utilizing its RNA medicines platform. Wave Life Sciences, Inc. was founded in 2012 and is headquartered in Cambridge, Massachusetts.
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