| Investor | Value | Of portfolio | Shares | Change | Quarter |
|---|---|---|---|---|---|
| Paulson & Co. · John Paulson | $719.5M | 27.9% | 1.34M | −3.7% | Q2 2026 |
| Renaissance Technologies | $24.7M | 0.03% | 45.94K | −36% | Q2 2026 |
From each investor's quarterly 13F filing with the SEC: positions at the quarter's end, reported up to 45 days later. All investors
No member of Congress has disclosed a MDGL trade since 2025.
From House and Senate STOCK Act reports. Members disclose trades, not holdings, as value ranges up to 45 days later, so amounts are estimates and “last move” is a hint at who still holds it, not a position. All recent congress trades
| Date | Insider | Transaction | Shares | Value |
|---|---|---|---|---|
| Sep 10, 2026 | Sibold William JohnChief Executive Officer | Sale at price 527.88 - 546.38 per share. | 11.6K | $6.24M |
| Aug 16, 2026 | Kelley Shannon TGeneral Counsel | Sale at price 514.97 per share. | 664 | $341.94K |
| Aug 13, 2026 | Reed John CDirector | Stock Award(Grant) at price 0.00 per share. | 647 | — |
| Jul 19, 2026 | Sibold William JohnChief Executive Officer | Sale at price 542.75 - 555.05 per share. | 2.5K | $1.37M |
| Jul 16, 2026 | Sibold William JohnChief Executive Officer | — | 50K | — |
| Jun 16, 2026 | Fouse Jacqualyn A.Director | Stock Award(Grant) at price 0.00 per share. | 454 | — |
| Jun 16, 2026 | Taub Rebecca A.Director | Stock Award(Grant) at price 0.00 per share. | 454 | — |
| Jun 16, 2026 | Levy Richard SDirector | Stock Award(Grant) at price 0.00 per share. | 454 | — |
| Jun 16, 2026 | Daly James M.Director | Stock Award(Grant) at price 0.00 per share. | 454 | — |
| Jun 16, 2026 | Brennan Daniel JDirector | Stock Award(Grant) at price 0.00 per share. | 404 | — |
| Jun 16, 2026 | Baker Bros Advisors, L.P.Unknown | Stock Award(Grant) at price 0.00 per share. | 1.8K | — |
| May 21, 2026 | Levy Richard SDirector | Sale at price 506.68 - 519.98 per share. | 5.7K | $2.93M |
| May 17, 2026 | Soergel DavidOfficer | Sale at price 515.90 per share. | 844 | $435.42K |
| Mar 5, 2026 | Taub Rebecca A.Director | Sale at price 431.94 per share. | 491 | $212.08K |
| Mar 5, 2026 | Sibold William JohnChief Executive Officer | Sale at price 431.94 per share. | 1.7K | $718.32K |
| Mar 5, 2026 | Dier Mardi CChief Financial Officer | Sale at price 425.08 - 437.65 per share. | 2K | $853.99K |
| Mar 5, 2026 | Huntsman Carole AOfficer | Sale at price 431.94 per share. | 419 | $180.98K |
| Mar 5, 2026 | Kelley Shannon TGeneral Counsel | Sale at price 431.94 per share. | 360 | $155.50K |
| Mar 3, 2026 | Sibold William JohnChief Executive Officer | Stock Award(Grant) at price 0.00 per share. | 15K | — |
| Mar 3, 2026 | Dier Mardi CChief Financial Officer | Stock Award(Grant) at price 0.00 per share. | 5.2K | — |
| Year | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Year |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | -16.0 | -11.7 | 21.2 | -1.2 | -3.9 | 8.0 | -13.0 | 15.6 | -6.7 | -9.9 | −22.1% | ||
| 2025 | 8.5 | 1.9 | -2.9 | 0.8 | -17.6 | 9.9 | -0.0 | 44.7 | 4.8 | -8.7 | 42.5 | -2.5 | +88.7% |
| 2024 | -6.3 | 9.0 | 13.1 | -23.6 | 15.8 | 18.6 | 1.6 | -13.2 | -14.1 | 22.2 | 26.5 | -6.0 | +33.4% |
| 2023 | -0.7 | -6.0 | -10.6 | 28.8 | -10.8 | -17.0 | -11.1 | -12.3 | -18.9 | -10.0 | 54.7 | 13.8 | −20.3% |
| 2022 | -32.1 | 61.3 | 5.7 | -28.7 | -5.2 | 7.8 | -12.2 | 14.8 | -9.9 | 9.0 | -1.0 | 314.0 | +242.5% |
| 2021 | 6.8 | 2.0 | -3.5 | 16.4 | -17.5 | -13.3 | -10.4 | -5.2 | -3.6 | -2.6 | 6.4 | 2.5 | −23.8% |
| 2020 | -8.9 | 3.8 | -22.5 | 25.3 | 38.6 | -2.4 | -9.4 | 5.0 | 10.2 | 7.2 | -8.2 | -4.8 | +22.0% |
| 2019 | 2.7 | 13.4 | -4.6 | -15.3 | -12.9 | 13.4 | -16.7 | 6.2 | -7.0 | 7.2 | 19.8 | -17.7 | −19.2% |
| 2018 | 61.7 | -15.1 | -7.3 | -3.1 | 134.7 | 5.3 | -8.1 | -6.9 | -10.5 | -10.9 | -39.4 | -2.5 | +22.8% |
| 2017 | 2.6 | 2.1 | -1.3 | 7.1 | -7.8 | 6.8 | -4.7 | 10.2 | 163.3 | 11.1 | 0.7 | 82.3 | +516.0% |
| 2016 | -31.4 | -4.2 | 4.3 | 66.7 | -12.5 | -25.7 | -17.6 | 53.9 | 9.9 | 30.1 | -3.0 | -6.9 | +21.6% |
| 2015 | -10.2 | 0.8 | -19.2 | 16.0 | -4.9 | 4.2 | -4.9 | -5.7 | -13.0 | -61.5 | -35.8 | -18.6 | −86.8% |
| 2014 | 1.9 | 15.7 | -30.3 | -2.3 | -2.6 | -0.2 | -3.4 | 1.3 | -24.8 | -1.7 | 7.1 | -16.4 | −49.4% |
| 2013 | 24.2 | -23.3 | 0.1 | 19.2 | -28.0 | -32.4 | 34.5 | -12.1 | 6.9 | -28.1 | 11.7 | 3.4 | −41.9% |
| 2012 | -1.3 | 3.7 | -8.2 | -0.9 | 10.6 | 13.7 | 34.4 | -10.6 | 16.0 | 3.3 | 2.5 | 11.8 | +93.1% |
| 2011 | -18.5 | 12.0 | -5.9 | 15.4 | -6.1 | -11.8 | -7.2 | -9.0 | -23.5 | 13.8 | 13.2 | 11.5 | −23.7% |
| 2010 | -17.4 | -6.5 | 10.2 | -5.8 | -22.9 | -13.7 | 18.9 | -13.7 | 44.0 | -7.3 | 15.9 | 42.7 | +20.9% |
| 2009 | 43.8 | -84.5 | 57.4 | 51.9 | 28.0 | -44.0 | 12.9 | 7.6 | 9.5 | -11.3 | 44.7 | 27.1 | −17.3% |
| 2008 | 17.6 | 12.4 | -8.7 | -17.1 | 4.3 | -12.9 | 29.0 | 12.6 | -14.0 | -7.1 | -25.1 | 15.5 | −8.7% |
| 2007 | -5.4 | 1.0 | 12.3 | -9.3 | -4.3 | -24.7 | 10.4 | 27.6 | -11.5 | -10.1 | −21.5% |
Madrigal Pharmaceuticals, Inc., a biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States. It offers Rezdiffra, a liver-directed thyroid hormone receptor beta agonist for treating MASH. The company was founded in 2016 and is headquartered in West Conshohocken, Pennsylvania.
Buy / hold / sell counts