| Jun 24, 2026 | Lynx1 Capital Management LpBeneficial Owner of more than 10% of a Class of Security | Purchase at price 4.12 per share. | 50.1K | $206.10K |
| Jan 7, 2026 | Chou WilliamChief Executive Officer | Sale at price 18.44 per share. | 4.1K | $75.16K |
| Jan 7, 2026 | Borthwick KathleenChief Financial Officer | Sale at price 18.44 per share. | 2.1K | $38.02K |
| Jan 7, 2026 | Chou WilliamChief Executive Officer | — | 10K | — |
| Jan 7, 2026 | Borthwick KathleenChief Financial Officer | — | 5K | — |
| Sep 14, 2025 | Lynx1 Capital Management LpBeneficial Owner of more than 10% of a Class of Security | Purchase at price 6.96 - 6.99 per share. | 32K | $223.74K |
| Jul 23, 2025 | Lynx1 Capital Management LpBeneficial Owner of more than 10% of a Class of Security | Purchase at price 5.44 - 5.74 per share. | 128.8K | $733.83K |
| Jun 25, 2025 | Orbimed Advisors, L.L.C.Beneficial Owner of more than 10% of a Class of Security | Sale at price 0.33 - 0.35 per share. | 583.7K | $197.24K |
| Apr 23, 2025 | Orbimed Advisors, L.L.C.Beneficial Owner of more than 10% of a Class of Security | Sale at price 0.32 - 0.34 per share. | 235.6K | $78.73K |
| Apr 16, 2025 | Orbimed Advisors, L.L.C.Beneficial Owner of more than 10% of a Class of Security | Sale at price 0.33 - 0.38 per share. | 149.1K | $49.70K |
| Feb 10, 2025 | Borthwick KathleenChief Financial Officer | Sale at price 0.53 per share. | 3.2K | $1.69K |
| Feb 9, 2025 | Borthwick KathleenChief Financial Officer | — | 8K | — |
| Jan 13, 2025 | Orbimed Advisors, L.L.C.Beneficial Owner of more than 10% of a Class of Security | Sale at price 0.60 - 0.66 per share. | 223.2K | $142.22K |
| Jan 7, 2025 | Orbimed Advisors, L.L.C.Beneficial Owner of more than 10% of a Class of Security | Sale at price 0.68 - 0.77 per share. | 147K | $103.31K |
| Dec 26, 2024 | Lynx1 Capital Management LpBeneficial Owner of more than 10% of a Class of Security | Purchase at price 0.65 per share. | 373.6K | $241.04K |
| Dec 19, 2024 | Orbimed Advisors, L.L.C.Beneficial Owner of more than 10% of a Class of Security | Sale at price 0.60 per share. | 230.3K | $138.19K |
| Dec 10, 2024 | Orbimed Advisors, L.L.C.Beneficial Owner of more than 10% of a Class of Security | Sale at price 0.80 - 0.84 per share. | 62.3K | $51.99K |
| Dec 5, 2024 | Orbimed Advisors, L.L.C.Beneficial Owner of more than 10% of a Class of Security | Sale at price 0.79 - 0.82 per share. | 97.1K | $77.34K |
| Nov 26, 2024 | Lynx1 Capital Management LpBeneficial Owner of more than 10% of a Class of Security | Purchase at price 0.56 - 0.71 per share. | 456.4K | $284.52K |
